After losing their mother to an illness at a young age, two young and talented alchemists, brothers Edward and Alphonse Elric, attempt the forbidden act of human transmutation to bring her back. But little did they know there was a heavy price to pay for breaking the ultimate taboo in alchemy. Edward loses his left leg after the transmutation fails, and his only remaining family, Alphonse, is taken from him. Desperate to bring his precious brother back, Edward sacrifices his right arm in exchange for Alphonse’s soul and successfully binds him into a suit of armor. The brothers must now embark on a journey to regain everything they have lost.